The Eczema Center
Eczema Primer

Chapter 1. Laboratory Studies
Laboratory studies have limited utility in diagnosing atopic dermatitis, but may be helpful in select cases. Patients with atopic dermatitis may have elevated serum immunoglobulin E (IgE) levels. This finding is not specific to atopic dermatitis though and may be seen with a variety of other disorders including asthma, allergies and the hyperimmunoglobulin E syndrome. Up to 20% of atopic dermatitis patients will have a normal serum IgE level, therefore a negative result does not rule-out a diagnosis of atopic dermatitis. Conversely, an elevated IgE level lends support to the diagnosis. Allergy testing may have a role in a subset of patients with atopic dermatitis.